Automatic Ampoule Filling and Sealing Machine


Ampoule Filling and Sealing Machine is used for filling and sealing of glass ampoules. Machine is widely uses in pharmaceutical, biotech, cosmetic, veterinary & chemical industry. We design Ampoule Filling and Sealing Machine as per our standard model as well as custom made models according to customer’s specific requirements.
Machine built on principal of slant travel of ampoules while filling and sealing to take care wide variation of ampoule neck dimensions, thicknesses and ovality of available ampoules.
Ampoule Filling and Sealing Machine is built on Stainless Steel square pipes frame & totally encompassed with Stainless Steel coverings in pleasing matt finish design. Large opening area configured on bottom side of the machine for absolute cleaning and maintenance of the machine.
The pendant type electrical control panel is lifted from machine for ease of operation and safety

Salient Features

  • Compact GMP model
  • Production output ranging from 30 ampoules/min. to 150 ampoules/min.
  • All contact parts made from AISI SS 316L & other Non-contact parts made from AISI SS 304.
  • Machine is suitable to fill 1ml to 20ml ampoules and minimum change over parts from 1ml to 20ml ampoule size
  • “No Ampoule – No Filling” system
  • Ampoule neck centering during gas flushing and filling operations
  • Possibility of nitrogen gas flushing before, during and after filling
  • Full accessibility allows easy maintenance
  • Machine equipped with pre-warming station
  • Minimum change over time, little maintenance & easy cleaning

Process Operation

The sterilized ampoule tray directly loaded in to slant hopper of the unit. The Synchronized star wheel delivers ampoules one by one on moving eccentric ampoule rack in single/two/four/six.
During the stoppage of rack sequentially pre-gassing, filling, post gassing, pre heating and final sealing is achieved. Duly filled sealed ampoules then collected on collection tray automatically without hand touch.

The machine performs the following operations

  • Ampoule feeding by in-feed hopper, star wheel and ampoules transfer into transport rack.
  • Two ampoules advanced per machine stroke.
  • Centering of ampoules necks during pre-heating, post heating, gas flushing and liquid filling.
  • Rotation of ampoules neck in the pre- heating and heating station.
  • Elimination of burdened-off ampoule tips by clippers and ejection into a separate container.

Technical Specification

Model AI-AFS 1 AI-AFS 2 AI-AFS 4 AI-AFS 6
No. of Head Single Two       Four Six
Ampoule Handling Range 1 ml to 20 ml 1 ml to 20 ml 1 ml to 10 ml 1 ml to 10 ml
Production Output 15 to 30 ampoules/minute 30 to 55 ampoules/minute 55 to 100 ampoules/minute 80 to 150 ampoules/minute
Filling Accuracy ± 1% ± 1% ± 1% ± 1%
Require Gas for Sealing LPG & Oxygen (O₂) LPG & Oxygen (O₂) LPG & Oxygen (O₂) LPG & Oxygen (O₂)
Nitrogen Flushing Pre & Post Nitrogen Flushing Available Pre & Post Nitrogen Flushing Available Pre & Post Nitrogen Flushing Available Pre & Post Nitrogen Flushing Available
Power Specification 0.5 H.P 1 H.P. 1 H.P. 1 H.P.
Electrical Characteristics 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System
Contact Parts Made from Stainless Steel 316L Made from Stainless Steel 316L Made from Stainless Steel 316L Made from Stainless Steel 316L
Non Contact Parts Made from Stainless Steel 304 Made from Stainless Steel 304 Made from Stainless Steel 304 Made from Stainless Steel 304
Overall Dimension 915mm (L) x
610mm (W) x
965mm (H)
915mm (L) x
760mm (W) x
965mm (H)
1200mm (L) x
1070mm (W) x
965mm (H)
1600mm (L) x
1400mm (W) x
1400mm (H)
* Specification offered is for reference purpose only.